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Τετάρτη 14 Μαΐου 2014

Life Sciences and Greece



Strong market fundamentals and a top-notch talent pool provide the opportunity for cost efficient medicine development in Greece.



Greece’s Life Sciences industry has been developing at a vigorous rate. Start-up and spin-off companies are emerging with new products and established players are increasingly pursuing international R&D collaborations for the development of competitive, technology-based products. Essential to this dynamic growth is the Greek R&D infrastructure, which includes internationally renowned Research Institutes and University Research Groups. Greece is proud to host world-class research teams, engaged in leading-edge Life Sciences Research and international collaborations with corporate and research players, in Europe and worldwide.

The Biotech market growth has been exceptionally strong. Total pharmaceutical spending in Greece, as a proxy for Biotech spending, has grown at an annual pace of 17.5% from 2000 to 2007, while the total annual healthcare expenditure in Greece from 2000 to 2006 has been growing at 11%. Greece boasts the largest number of pharmacies per capita in Europe, with 94.2 pharmacies per 100,000 inhabitants. The strong growth in pharma spending in Greece is supported by the social security safety net, through which most pharma expenditures are reimbursed by the Greek state. The Greek state pharma expenditure covered 90% of the total pharma expenditure in 2006. The growth in pharma expenditure is estimated to continue as Greece’s population ages, Greece smoking rate remains high, obesity rises, and sedentary lifestyles take hold.
Despite the fact that Greece is a net importer of pharmaceuticals, domestic production of medicines has grown by 11.1% annually from 2000 to 2007. Furthermore, Greece’s highly effective drug management system has reduced counterfeit medicines to a minimum compared with other European Union countries.

Healthcare services have also been growing strongly. Private hospitals have increased their market share and the demand for privately funded health care is proving strong. Obstetrics is one of the most rapidly growing private healthcare services sectors. Greek private hospitals are expanding into neighbouring Southeast European countries and analysts estimate that Greece could become an attractive destination for ‘health tourists’ seeking high quality healthcare services at competitive rates.

Regional Hub for Clinical TrialsGreece has established itself as a regional hub for clinical trials and most major international pharmaceutical companies conduct clinical trials in Greece. Approximately 300 protocols are approved each year, with about 700 state university and research institutions overseeing these protocols. The average cost per clinical trial per patient stands between €2,000 - €3,000
Concrete Investment Opportunities
Greece offers a unique investment opportunity to international pharma companies to enhance and support their main growth driver: the development of new medicines. With an exceptional talent pool at very competitive rates, top universities and research facilities to conduct R&D, and a competitive overhead structure, Greece is an ideal location for a research team developing and testing a new medicine or for developing medical and diagnostic devices. And, as underlined, a conducive environment for clinical trials presents an opportunity for biotech companies looking to the international market to gain the extra edge over the competition.

Establishing regional headquarters in Greece for the Southeast Europe, Middle East or North Africa region allows companies to tap into highly educated, strongly motivated human capital with strong multinational corporate ethics.

Biovista Inc. Named Top Innovator in Life Sciences
Biovista Inc. was awarded the 2009 Top Innovator Presentation Award in Healthcare at the 2009 New England Venture Summit, held December 8, 2009 in Dedham, Massachusetts, USA. The award, which recognizes cutting edge private companies driving the future of innovation, was granted to Biovista, which competed with over 50 other privately held companies that play a leading role in innovation in the Technology, Life Sciences and Clean-tech sectors. Biovista's repositioning programmes leverage the company's technology platform to identify suitable drugs and reposition them in isolation or in combination with other drugs to therapeutic areas currently not covered by existing products. By selecting drugs that already satisfy basic toxicity, ADME and related criteria, Biovista is able to deliver significant value at reduced cost and in dramatically shorter time frames than is normally the case.
EMBIO Diagnostics Captures 1st Prize in Entrepreneurship Competition
EMBIO Diagnostics won the 1st prize of the 6th Cyprus Entrepreneurship Competition. EMBIO focuses on the development of sophisticated, portable cell biosensors for the detection of pesticides, biological warfare, animal/ human viruses & inflammation markers by means of membrane and genetic engineering. Two landmark products of the company are the Bioelectric Recognition Assay (BERA) cell biosensors and the Molecular Identification through Membrane Engineering (MIME) technology, which are widely appreciated as standard analysis tools for mass screening of chemical and biochemical compounds.
Forth Photonics Funding for Further Growth
Forth Photonics has completed its second round of fundraising with a new investment of €7.6m. The newly-raised funds are expected to take Forth Photonics’ first product through to full commercialisation. Forth Photonics will use the funds to commercialise its medical device, DySIS (Dynamic Spectral Imaging System), which is the only medical device to use dynamic spectral imaging technology to assist gynecologists in the detection and mapping of precancerous and cancerous lesions of the cervix. The use of DySIS has been shown in clinical trials to significantly increase the sensitivity of pre-cancerous lesion detection compared with traditional methods.
Advantages of Investing in Greece's Life Science market
•Strong market fundamentals
•High quality personnel
•Business-conducive environment
•R&D support
•Attractive investment opportunities
•Attractive funding opportunities
Strong Market Fundamentals
The Life Sciences market in Greece has been displaying strong growth in recent years, with pharmaceutical expenditure growing at a pace close to 20% annually, supported by a strong state social security net. This trend is expected to continue, driven by the demographic characteristics of the Greek population.
Human Capital
The Greek workforce has a high percentage of graduate and post-graduate degrees:

Workforce by level of education



Source: National Statistic Service


Greece has one of the highest number of doctors per capita in the world, an important statistic when using physicians as a proxy for medical workers.


Doctors per 1,000 habitants
Source: World Development Indicators Database


Conducive Business Environment
Greece's government has given increased emphasis to R&D activities and is committed to investing in the advance of technology by developing the country’s considerable intellectual capital. Innovation is a key priority and the private sector is increasingly devoting more resources to foster new and marketable products and services. Cooperation among universities and business, the public and private sector, and research and production has been growing in recent years, providing the impetus for advances in innovation. The Thermi Incubator in Thessaloniki and the Technological Parks in Athens, Thessaloniki, Patras, Volos, Herakleio and Ioannina are examples of institutes that support cutting edge R&D in Greece.
R&D Support
The Institute for Molecular Biology and Biotechnology (IMBB)The Institute for Molecular Biology and Biotechnology (IMBB) was founded in 1983 and is one of the Institutes of the Foundation for Research and Technology – Hellas (FORTH). FORTH, among Greece’s leading and largest Research Centres, comprises seven Research Institutes, located throughout the country. FORTH has become one of the top European research centers, thanks to its high impact research results and its valuable socioeconomic contribution. Its track record in nurturing startups/spin-offs and establishing RTD partnerships with industrial partners are also notable. IMBB was ranked first in evaluations of Greek Research Institutes carried out by the Greek Secretariat for Research and Technology.

Biomedical Research Foundation of Academy of Athens (BRFAA)Established in 2003, BRFAA supports basic science and clinical research through its research programmes in immunology, gene expression, cell biology, stem cells, cancer, metabolic diseases, development and the function of the cardiovascular and the nervous systems. It comprises of two Basic Sciences Centres focusing on the understanding of basic aspects of biological pathways and Centres for Immunology and Transplantation, Neurobiology, Experimental Surgery, Clinical Research and Environmental Health.

BSRC Al. Fleming
Established in 1998, BSRC Al. Fleming is one of Greece’s leading specialist research organisations in Biomedical Sciences. Fleming has a scientific staff of over 120, organised into 15 research groups in four Research Institutes: Immunology; Molecular Biology & Genetics; Molecular Oncology and Cellular & Developmental Biology. A notable feature of Fleming’s research profile is the central role of the use of animal models of human disease, particularly mouse models. As Greece’s largest operational mouse facility, it is a leading centre of mouse research in Europe.
Attractive Funding Opportunities
International investors planning to penetrate the Greek biotechnology and pharmaceutical markets may benefit from funding opportunities provided both from public and private sources. A number of National Strategic Reference Program funding programmes allow for the enhancement of technology development realisation of R&D projects, for the spawning of spin-offs and spin-outs.

In addition, international companies will find in Greece an entire range of seed capital funding, venture capital funding and private equity funding required to finance growth. The Athens stock exchange is an attractive option for drawing equity capital, as there are many listings with international tranches.

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